Beta thalassemia is a very common type of blood disease seen in Turkey as well as other mediterranean countries. Although carrier frequency for this disease may rise up to 10 % in some regions, but it is 2-3 % on average.

Because of a high intermarriage , mariage between relatives, rate in Turkey ( about 21% of all marriages) , a lot of pregnancies become affected and many are ended with abortion. According to research fiindings, IVS-I 110 is the most frequently observed mutation type.